Creutzfeldt-Jakob disease

1 Brote Activo

Creutzfeldt-Jakob disease (CJD) is a rare, rapidly progressive, and fatal neurodegenerative disorder. It is caused by prions, which are abnormally folded proteins that induce normal proteins in the brain to misfold. CJD primarily affects older adults (sporadic form) worldwide, leading to rapid mental and physical deterioration.

1
Países Afectados
Monitoring
Casos Recientes (30 días)
1
Brotes Activos
230d ago
Última Actualización
Open Web App

¿Qué es Creutzfeldt-Jakob disease?

Creutzfeldt-Jakob disease was first described in the early 1920s by German neurologists Hans Gerhard Creutzfeldt and Alfons Maria Jakob. Its significance grew with the understanding of transmissible spongiform encephalopathies (TSEs), particularly the link between **variant CJD** and bovine spongiform encephalopathy (BSE) in the 1990s, highlighting the unique nature of prion diseases.

Síntomas

  • Rapidly progressive dementia (memory loss, impaired judgment, confusion)
  • Myoclonus (involuntary muscle jerks)
  • Ataxia (loss of coordination, difficulty walking)
  • Vision problems (e.g., double vision, blurred vision)
  • Psychiatric symptoms (depression, anxiety, mood swings)
  • Speech impairment

Transmisión

CJD is not contagious through casual contact. Most cases are **sporadic**, meaning they occur spontaneously without a clear cause. Transmission can also occur through medical procedures (**iatrogenic CJD**) involving contaminated brain tissue or instruments, or through inheritance (**familial CJD**); **variant CJD (vCJD)** is acquired by consuming contaminated beef products.

Período de Contagio: Varies by disease

Prevención

  • Strict sterilization of surgical instruments used on brain or spinal cord tissue.
  • Avoiding use of human-derived hormones or dura mater grafts that may be contaminated.
  • Screening blood donors to exclude individuals at risk for CJD or variant CJD (vCJD).
  • For vCJD, avoiding consumption of beef products potentially contaminated with bovine spongiform encephalopathy (BSE, \"mad cow disease\").

Live Creutzfeldt-Jakob disease Global Case Map

1 country with reported activity. Updated from real-time surveillance data.

No reports
Low activity
High activity

Brotes Activos y Casos Recientes

Inteligencia en tiempo real de monitoreo global de salud y vigilancia impulsada por IA

Fuentes de datos: BEACON, ProMED, OMS, CDC y más de 50 agencias nacionales de salud

✓ Datos en vivo actualizados en tiempo real desde fuentes de salud globales

Estimating future variant Creutzfeldt-Jakob disease cases in the UK: a cohort-based probabilistic model

United Kingdom 2025-11-11
Activo

Variant Creutzfeldt-Jakob disease (vCJD) is a fatal prion disorder linked to dietary exposure to bovine spongiform encephalopathy (BSE). The epidemic peaked in the early 2000s, and no new cases have been reported in the UK since 2016. However, uncertainties remain regarding potential future cases, particularly in individuals with non-MM prion protein gene codon 129 genotypes, and possible secondary transmission via blood transfusion. We aimed to update risk estimates with recent data, informed by a probabilistic modelling approach. We developed a cohort-based probabilistic model for variant CJD incidence incorporating genotype-specific attack rates and incubation periods, accounting for competing mortality risks. Model parameters were calibrated using historical case data and life-table an...
Read Full Article

View Live Alerts in Web App

Rastree Creutzfeldt-Jakob disease y más de 200 otras enfermedades con alertas personalizadas

Recursos Expertos y Referencias

Información confiable de las principales organizaciones de salud

CDC

Orientación oficial de los Centros para el Control y la Prevención de Enfermedades de EE. UU.

Ver Recursos del CDC →

WHO

Vigilancia global de enfermedades y directrices de la Organización Mundial de la Salud

Ver Recursos de la OMS →

Investigación

Últimas investigaciones revisadas por pares y estudios clínicos

Ver Investigación →

Contenido Revisado Médicamente

La información sobre enfermedades en Virus Watcher es revisada por nuestro Epidemiólogo Jefe, ex analista principal del CDC para el pronóstico FluSight. Los datos de brotes se agregan de fuentes verificadas incluyendo BEACON, ProMED, OMS, CDC y más de 50 agencias nacionales de salud. Esta información es con fines educativos y no debe reemplazar el asesoramiento médico profesional.

Última revisión: 2026-06-29

Anticípese a las Creutzfeldt-Jakob disease Brotes

Obtenga alertas e inteligencia en tiempo real sobre Creutzfeldt-Jakob disease y más de 200 otras enfermedades. Utilizado por sistemas de salud, servicios de emergencias médicas, escuelas y viajeros de todo el mundo.

Open Web App
Virus Watcher