Hemolytic Uremic Syndrome (HUS) is a serious complication characterized by the destruction of red blood cells (hemolytic anemia), low platelet count (thrombocytopenia), and acute kidney injury. It most commonly develops after an infection with Shiga toxin-producing E. coli (STEC), primarily affecting young children following diarrheal illness.
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Hemolytic Uremic Syndrome was first formally described in 1955 by Dr. Conrad Gasser and his colleagues. Its strong association with Shiga toxin-producing E. coli (STEC), particularly the O157:H7 strain, was firmly established following outbreaks in the 1980s, highlighting its significant link to foodborne pathogens.
HUS itself is not directly transmissible, but the underlying STEC infection that often triggers it is primarily spread through the fecal-oral route. This includes consuming contaminated food (e.g., undercooked ground beef, unpasteurized dairy/juices, contaminated produce), contaminated water, or direct contact with infected animals. Person-to-person transmission is also possible, especially in childcare settings and households, if hygiene practices are insufficient.
Contagious Period: Varies by disease
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Our AI-powered surveillance hasn't detected significant Hemolytic Uremic Syndrome activity in the past 30 days.
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Currently, Hemolytic Uremic Syndrome case counts are within baseline expectations globally. However, diseases can emerge rapidly, which is why continuous monitoring is critical.
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Official guidance from the U.S. Centers for Disease Control and Prevention
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View WHO Resources →Disease information on Virus Watcher is reviewed by our Chief Epidemiologist, a former CDC lead analyst for FluSight forecasting. Outbreak data is aggregated from verified sources including BEACON, ProMED, WHO, CDC, and 50+ national health agencies. This information is for educational purposes and should not replace professional medical advice.
Last reviewed: 2026-06-03
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