Syphilis

9 Active Outbreaks

Congenital Syphilis is a serious bacterial infection caused by Treponema pallidum, passed from a pregnant mother to her unborn child. It primarily affects infants born to mothers with untreated or inadequately treated syphilis, leading to severe and potentially life-threatening health problems.

7
Countries Affected
1,640
Recent Cases (30d)
9
Active Outbreaks
33d ago
Last Updated

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What is Syphilis?

Syphilis has a long and complex history, with congenital transmission recognized centuries ago, impacting families long before its bacterial cause was identified. The discovery of *Treponema pallidum* in 1905 by Schaudinn and Hoffmann, and later the introduction of penicillin in the mid-20th century, revolutionized the prevention and treatment of congenital syphilis, dramatically reducing its incidence.

Symptoms

  • Early Congenital Syphilis (often within the first 2 years of life):
  • Skin rashes (often on palms and soles)
  • 'Snuffles' (rhinitis with nasal discharge)
  • Enlarged liver and spleen (hepatosplenomegaly)
  • Jaundice
  • Bone abnormalities (osteochondritis, periostitis)
  • Anemia
  • Late Congenital Syphilis (after 2 years of age, if untreated earlier):
  • Hutchinson's teeth (notched, peg-shaped incisors)
  • Interstitial keratitis (corneal inflammation, leading to vision loss)
  • Sensorineural deafness (auditory nerve damage)
  • Saddle nose deformity
  • Saber shins (anterior bowing of tibias)
  • Neurological problems (e.g., developmental delays, seizures)

Transmission

Congenital Syphilis is transmitted vertically from a pregnant individual to their fetus across the placenta. This can occur at any stage of pregnancy if the mother has untreated or inadequately treated syphilis. The risk of transmission is highest during the primary and secondary stages of maternal syphilis.

Contagious Period: Varies by disease

Prevention

  • Routine Syphilis Screening for all pregnant individuals during their first prenatal visit, and again in the third trimester and at delivery in high-risk areas or for high-risk individuals.
  • Prompt and Adequate Treatment of infected pregnant individuals with penicillin as soon as syphilis is diagnosed.
  • Treatment of Sexual Partners of infected pregnant individuals to prevent reinfection.
  • Abstinence or Safe Sex Practices (e.g., consistent and correct condom use) to prevent syphilis acquisition.

Live Syphilis Global Case Map

7 countries with reported activity. Updated from real-time surveillance data.

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1 state with reported activity. Click a state for detailed surveillance.

Active Outbreaks & Recent Cases

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Denmark 1st in EU to eliminate mother-to-child HIV, syphilis transmission: WHO

United States, Alaska 2026-03-01
Active

Agency says milestone reflects decades of strong maternal health services, universal care

The World Health Organization (WHO) has certified Denmark as the first EU country to eliminate mother-to-child transmission of HIV and syphilis, recognizing sustained efforts to ensure babies are born free of the infections.

"The elimination of mother-to-child transmission of HIV and syphilis marks a major public health achievement for Denmark," WHO Director-General Tedros Adhanom Ghebreyesus said in a sta

πŸ“° 21 news sources reporting on this story.

πŸ”— Read more at Daily Tribune

STI Cases Surge in Brazil After Carnival Screening

Brazil 2026-02-17
Active

During Carnival 2026 (12–18 Feb 2026) in Salvador, Bahia state, mass screening detected 324 sexually transmitted infections across Salvador, Brumado, and Porto Seguro, including 26 HIV cases and 370 syphilis cases, among more than 24 000 rapid tests administered. Event-based surveillance successfully identified undiagnosed infections in high-density crowds, and immediate treatment was initiated for 88 syphilis patients. However, HIV-positive individuals require follow-up linkage to specialist care within the health network.

Source: BEACON - View Full Report

Argentina: Syphilis Cases Surge, Youth Most Affected

Argentina 2026-02-21
Active

Argentina reported 55 183 confirmed syphilis cases in 2025, a 71% increase compared to 2020–2024, with rises also observed in maternal and congenital infections and the highest burden among young people aged 20–29 years. The continued increase reflects both sustained transmission in sexually active populations and expanded detection through strengthened surveillance and primary care testing, while asymptomatic early infections contribute to ongoing spread. Although syphilis is treatable with penicillin, current trends underscore the need for sustained screening, timely treatment, partner notification, and reinforced prevention efforts, particularly among young adults and pregnant women.

Source: BEACON - View Full Report

International Condom Day is this Friday, and this year, the day comes with a cautionary reminder for South Africans that we are seeing rising rates of STIs - South Africa Today

South Africa 2026-02-13
Active

Condoms extend the triple protection that still works Johannesburg: 11 February 2026: The AIDS Healthcare Foundation South Africa (AHF) invites communities to celebrate International Condom Day (ICD) with the simple message - "Just Use It!" - and put condoms, one of the most powerful and cost-effective tools in HIV and STI prevention, back in the spotlight. This year, the day comes with a cautionary reminder for South Africans that we are seeing rising rates of STIs - a pattern repeated across the globe. The surge in STI rates worldwide, particularly syphilis, is not a mystery; it is what happens when global funding diminishes, and condoms are not prioritised for prevention. Without an immediate course correction, HIV will soon follow. Each condom used helps safeguard decades of progress i...
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Australians are dying from a disease that was almost eliminated years ago

Australia 2026-06-15
Active

This is the damage late-stage syphilis can do to bones. The Victorian-era sexually transmitted infection is preventable and curable, so why are infection rates rising in Australia? Turning over old bones, Emeritus Professor Maciej Henneberg is trying to get to the bottom of an old disease that has resurfaced in Australia. Like a cold case detective, he's excavated remains upturned by development and construction all over the world. The bioarchaeologist is scouring remains for signs of syphilis in past populations. "[Advanced syphilis] causes body changes, growth of additional bone, especially the leg bones, and some destruction of other bones," Professor Henneberg explains. Inside South Australia's Vernon-Roberts Museum, where tightly controlled bone samples are held for teaching, Professo...
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AHF Nigeria celebrates international condom day

Nigeria 2026-02-10
Active

A global non-profit organisation providing cutting-edge medicine and advocacy, AIDS Healthcare Foundation (AHF) Nigeria has invited communities to celebrate International Condom Day (ICD) with the simple message - "Just Use It!" - and put condoms, one of the most powerful and cost-effective tools in HIV and STI prevention, back in the spotlight. In a statement, it said: "This year's ICD celebration is taking place in Akwa, Anambra state and at the University of Abuja, Faculty of Media and Communications Study and will combine fun, creativity, and education with free condom distribution, reinforcing the message that protecting s3xual health should be accessible, stigma-free, and empowering for everyone. "The surge in STI rates worldwide, particularly syphilis, is not a mystery -- it is what...
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5,500-year-old DNA shows syphilis was rooted in the Americas, before Columbus

World, World 2026-01-22
Active

From a 5,500-year-old human shinbone, scientists have discovered a close cousin of the pathogen that causes syphilis, providing the oldest evidence yet that the disease has ancient roots in the Americas, millennia before European contact. A historical and scientific debate has raged about the origi... Source: The Boston Globe - Read Full Article

bioLytical's iStatis Syphilis Antibody Test Now Included in the Australian Register of Therapeutic Goods (ARTG)

World, World 2025-10-12
Active

Expanding access to fast, accurate syphilis testing to support Australia's public health response. iStatis Syphilis Antibody Test Get the latest news delivered to your inbox Sign up for The Manila Times newsletters By signing up with an email address, I acknowledge that I have read and agree to... Source: The Manila times - Read Full Article

Dozens of babies die of syphilis in Hungary as cases soar globally

World, World 2025-12-07
Active

Although syphilis is easily treatable with antibiotics - chiefly penicillin - women who are homeless, use drugs or are living in poverty are more likely to go undetected. Children born with the infection are treated with penicillin, administered through an IV drip for a 10-day period. Adults are al... Source: NZ Herald - Read Full Article

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Expert Resources & References

Trusted information from leading health organizations

CDC

Official guidance from the U.S. Centers for Disease Control and Prevention

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WHO

Global disease surveillance and guidelines from the World Health Organization

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Research

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Medically Reviewed Content

Disease information on Virus Watcher is reviewed by our Chief Epidemiologist, a former CDC lead analyst for FluSight forecasting. Outbreak data is aggregated from verified sources including BEACON, ProMED, WHO, CDC, and 50+ national health agencies. This information is for educational purposes and should not replace professional medical advice.

Last reviewed: 2026-07-18

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