Thrombocytopenia syndrome

2 Active Outbreaks

Thrombocytopenia syndrome (also known as Severe Fever with Thrombocytopenia Syndrome, SFTS) is a viral infection characterized by sudden fever, digestive issues, and significantly low platelet and white blood cell counts. It is caused by the SFTS virus and primarily affects people in East Asian countries, transmitted by ticks.

2
Countries Affected
57
Recent Cases (30d)
2
Active Outbreaks
31d ago
Last Updated

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What is Thrombocytopenia syndrome?

SFTS was first identified in 2009 in rural areas of China, following a cluster of patients presenting with unexplained fever and low platelet counts. Researchers subsequently isolated the causative agent, the SFTS virus. This discovery helped to characterize a previously unknown infectious disease prevalent in certain East Asian regions.

Symptoms

  • Early Stage: Sudden high fever, fatigue, muscle aches, headache, nausea, vomiting, diarrhea, abdominal pain.
  • Severe Cases: Bleeding manifestations (e.g., skin spots, nosebleeds), enlarged lymph nodes, neurological issues, multi-organ dysfunction.

Transmission

The primary mode of transmission for SFTS is through the bite of infected ticks, particularly the *Haemaphysalis longicornis* species. While rare, human-to-human transmission can occur through direct contact with blood or other body fluids from an acutely ill patient, especially in healthcare settings or during post-mortem examination.

Contagious Period: Varies by disease

Prevention

  • Avoid tick bites: Wear long clothing, use insect repellents (e.g., DEET, permethrin) when outdoors.
  • Check body for ticks after outdoor activities and remove them promptly and correctly.
  • Avoid contact with wild animals, especially small mammals, which can carry ticks.
  • Currently, no human vaccine is available for SFTS.

Live Thrombocytopenia syndrome Global Case Map

2 countries with reported activity. Updated from real-time surveillance data.

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Active Outbreaks & Recent Cases

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Severe fever with thrombocytopenia syndrome, Japan

Japan 2026-06-17
Active

The number of severe fever with thrombocytopenia syndrome (SFTS) cases reported in Japan has steadily increased in recent years, and the pathogen's geographic range has expanded. A concurrent increase in pet infections was also observed.

Source: BEACON - View Full Report

A replicating RNA vaccine protects against severe fever with thrombocytopenia syndrome virus infection in mice - npj Vaccines

World, World 2025-10-16
Active

SFTSV YL-1 causes lethal disease in C57BL/6J mice with transient suppression of type I interferon (IFN) We first established a lethal challenge model for SFTSV for the evaluation of candidate vaccines. SFTSV causes little-to-no disease in wild-type (WT) mice, although mice deficient in type I IFN r... Source: Nature - Read Full Article

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Expert Resources & References

Trusted information from leading health organizations

CDC

Official guidance from the U.S. Centers for Disease Control and Prevention

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WHO

Global disease surveillance and guidelines from the World Health Organization

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Research

Latest peer-reviewed research and clinical studies

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Medically Reviewed Content

Disease information on Virus Watcher is reviewed by our Chief Epidemiologist, a former CDC lead analyst for FluSight forecasting. Outbreak data is aggregated from verified sources including BEACON, ProMED, WHO, CDC, and 50+ national health agencies. This information is for educational purposes and should not replace professional medical advice.

Last reviewed: 2026-07-18

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