Vancomycin-resistant Staphylococcus aureus in Michigan

• Skin and Soft Tissue Infections: Redness, swelling, pain, warmth, pus-filled lesions (e.g., boils, abscesses).
• More Serious Infections:
• Pneumonia: Fever, chills, cough, shortness of breath.
• Bloodstream Infections (Bacteremia): Fever, chills, general malaise.
• Bone Infections (Osteomyelitis): Pain, swelling, fever over affected bone.
• Heart Valve Infections (Endocarditis): Fever, fatigue, shortness of breath.

VRSA primarily spreads through direct contact with an infected person's wounds, bodily fluids, or contaminated skin. It can also be transmitted indirectly by touching contaminated surfaces or objects in healthcare environments. Healthcare workers' hands often play a role in transmission if proper hygiene is not maintained, and individuals can carry *Staphylococcus aureus* asymptomatically on their skin or in their nostrils.

• Rigorous Hand Hygiene: Frequent handwashing with soap and water or use of alcohol-based hand sanitizer, especially in healthcare settings.
• Environmental Cleaning: Regular cleaning and disinfection of surfaces and equipment in healthcare facilities.
• Isolation Precautions: Implementing contact precautions for infected patients in hospitals to prevent spread.
• Judicious Antibiotic Use: Healthcare providers prescribing antibiotics appropriately to minimize the development of resistance.
• No vaccine is currently available specifically for *Staphylococcus aureus* infections.