West Africa
Reviewed by Alexander Webber, Chief Epidemiologist · Updated 2026-08
Nigeria carries among the highest infectious disease burdens in West Africa, with year-round malaria transmission across all regions and yellow fever vaccination required for all travelers. Lassa fever is endemic in several states, and meningococcal disease outbreaks occur periodically in the northern belt. Food and water safety is a major concern throughout the country, and cholera outbreaks recur frequently.
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High risk throughout all of Nigeria year-round. Falciparum malaria is dominant. Resistance to chloroquine is widespread. Atovaquone-proguanil or doxycycline are the preferred prophylaxis agents. Prophylaxis is strongly recommended for all travelers regardless of destination within Nigeria.
Tap water is unsafe throughout Nigeria. Drink only commercially bottled or boiled water. Avoid ice, raw or undercooked foods, and street food unless from verified clean sources. Foodborne illness is common even in Lagos hotels.
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