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Latin America

Peru Travel Health

Reviewed by Alexander Webber, Chief Epidemiologist · Updated 2026-08

Peru's health risks vary dramatically by altitude zone. The Amazon lowlands carry risk for malaria, yellow fever, dengue, and leishmaniasis, while the Andean highlands present risk for altitude sickness and cold exposure. Lima and the coastal desert strip are generally low risk for vector-borne disease. Food and waterborne illness including traveler's diarrhea, typhoid, and hepatitis A are risks throughout the country, particularly at lower altitudes.

Food Safety: Moderate Risk Tap Water: Unsafe Malaria Risk Present

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Vaccines for Peru

CDC Recommended

  • Yellow Fever (for Amazon basin travel)
  • Hepatitis A
  • Typhoid
  • Hepatitis B
  • Rabies (for jungle travel or animal contact risk)
  • Malaria prophylaxis (for Amazon region)

Source: CDC Travelers' Health β€” Peru

Malaria Risk

Present in Amazon basin departments including Loreto, Ucayali, San Martin, and Madre de Dios. Predominantly P. vivax; P. falciparum present in border regions. No malaria risk in Lima, Cusco, Machu Picchu, or the highlands above 2,500 meters.

Food and Water Safety

Moderate Risk Tap water: not safe to drink

Ceviche from reputable establishments is generally safe but raw fish from informal vendors carries risk. Avoid tap water, ice of unknown origin, and raw produce washed in tap water throughout the country.

Key Health Tips for Peru

  • Acclimatize gradually to high altitude β€” Cusco sits above 3,400 meters and altitude sickness is common even in healthy travelers.
  • Carry acetazolamide (Diamox) if your itinerary includes rapid ascent above 3,000 meters; discuss with your physician before travel.
  • Yellow fever vaccination is required for entry into some Amazon nature reserves β€” verify requirements before departure.
  • Use bottled water throughout Peru including in major cities and tourist hubs.

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