What vaccines do I need for Cambodia?

Recommended by the CDC: Hepatitis A, Hepatitis B, Typhoid, Japanese Encephalitis (especially rural travel or long stays), Rabies (recommended for rural travel).

Is tap water safe to drink in Cambodia?

Tap water is not safe to drink in Cambodia. Drink bottled or treated water throughout your trip, including in resort areas.

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Southeast Asia

Cambodia Travel Health

Reviewed by Alexander Webber, Chief Epidemiologist · Updated 2026-08

Cambodia is home to the iconic Angkor Wat temple complex and the Tonle Sap lake. The country has a developing healthcare system, with Phnom Penh and Siem Reap offering the best medical facilities. Malaria risk is significant outside tourist centers, and dengue is endemic nationwide. Flooding during monsoon season creates additional risks.

Food Safety: High Risk Tap Water: Unsafe Malaria Risk Present

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Vaccines for Cambodia

CDC Recommended

Hepatitis A
Hepatitis B
Typhoid
Japanese Encephalitis (especially rural travel or long stays)
Rabies (recommended for rural travel)

Source: CDC Travelers' Health — Cambodia

Malaria Risk

Moderate to high risk in forested regions, particularly along the Thai and Lao borders (Pailin, Preah Vihear, Ratanakiri, Mondulkiri). Low risk in Phnom Penh, Siem Reap, and coastal areas.

Food and Water Safety

High Risk Tap water: not safe to drink

Food hygiene standards are lower than neighboring countries. Stick to hot, freshly cooked food and avoid raw produce, street ice, tap water, and raw or undercooked meat and seafood. Traveler's diarrhea is common. Bottled water is essential.

Key Health Tips for Cambodia

Malaria chemoprophylaxis is strongly recommended for travel outside Phnom Penh and Siem Reap, especially to border provinces.
Dengue is a year-round risk — use DEET repellent faithfully.
Medical facilities are very limited outside major cities — carry a comprehensive travel health kit.
Travel medical evacuation insurance is essential — serious cases require evacuation to Bangkok or Singapore.

Disease Risks in Cambodia

Official Resources

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