East Africa
Reviewed by Alexander Webber, Chief Epidemiologist · Updated 2026-08
Ethiopia's health risk profile varies dramatically by altitude and region. Addis Ababa sits above 2,300 meters and carries minimal malaria risk, but lowland areas including the Omo Valley, Gambella region, and Afar carry high transmission. Travelers frequently visit both highland historic sites and lowland wildlife areas, requiring careful prophylaxis planning. Food and water safety is a major concern nationwide.
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Malaria risk is altitude-dependent. No risk in Addis Ababa and highlands above 2,500 meters. High risk in lowlands below 2,000 meters including the Rift Valley, Gambella region, and Omo Valley. If your itinerary includes lowland destinations, prophylaxis is strongly recommended.
Tap water is unsafe throughout Ethiopia. Drink only bottled or boiled water. Avoid raw produce, fresh juices, ice, and raw meat dishes including kitfo (raw minced beef), which carries significant risk for travelers without established immunity.
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