West Africa
Reviewed by Alexander Webber, Chief Epidemiologist · Updated 2026-08
Ghana presents high infectious disease risk for travelers, with malaria transmission occurring year-round throughout the entire country. Yellow fever vaccination is required for entry. Waterborne and foodborne illnesses including typhoid, hepatitis A, and cholera are common, particularly outside of Accra. Travelers to rural areas face additional risks from Lassa fever and other viral hemorrhagic fevers endemic to the region.
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Source: CDC Travelers' Health β Ghana
High risk throughout Ghana year-round, including in Accra. Falciparum malaria predominates and drug resistance is present. Prophylaxis is strongly recommended for all travelers. Atovaquone-proguanil or doxycycline are preferred.
Do not drink tap water anywhere in Ghana. Use sealed bottled water only. Avoid ice, raw produce washed in tap water, and street food unless preparation standards can be verified. Food safety varies widely even in Accra.
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