East Africa
Reviewed by Alexander Webber, Chief Epidemiologist · Updated 2026-08
Uganda carries a high burden of malaria, which is present year-round throughout the country including at altitude. Yellow fever vaccination is required for entry, and travelers face additional risks from typhoid, hepatitis A, and schistosomiasis in freshwater environments. Travelers visiting gorilla trekking areas in Bwindi or Mgahinga should be aware of rabies risk from wildlife. Ebola and Marburg outbreaks have occurred periodically in Uganda and travelers should monitor current health advisories.
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Source: CDC Travelers' Health β Uganda
High risk throughout the entire country year-round, including Kampala and high-altitude areas above 2,000 m. P. falciparum is the predominant species. CDC recommends atovaquone-proguanil, doxycycline, or mefloquine for chemoprophylaxis.
Tap water is not safe to drink; use sealed bottled or boiled water. Avoid raw or undercooked foods, street food prepared in unsanitary conditions, and unpasteurized dairy. Avoid swimming or wading in freshwater lakes and rivers due to schistosomiasis risk, including Lake Victoria.
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